BAY 41-2272, a direct activator of soluble guanylate cyclase, reduces right ventricular hypertrophy and prevents pulmonary vascular remodeling during chronic hypoxia in neonatal rats. [electronic resource]
Producer: 20061130Description: 135-44 p. digitalISSN:- 0006-3126
- Animals
- Animals, Newborn
- Chronic Disease
- Enzyme Activation -- drug effects
- Female
- Guanylate Cyclase -- metabolism
- Hypertension, Pulmonary -- drug therapy
- Hypertrophy, Right Ventricular -- pathology
- Hypoxia -- complications
- Lung -- blood supply
- Organ Size
- Pregnancy
- Pulmonary Artery -- drug effects
- Pyrazoles -- pharmacology
- Pyridines -- pharmacology
- Rats
- Rats, Sprague-Dawley
- Vasodilation -- drug effects
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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