BAY 41-2272, a direct activator of soluble guanylate cyclase, reduces right ventricular hypertrophy and prevents pulmonary vascular remodeling during chronic hypoxia in neonatal rats.

Deruelle, Philippe

BAY 41-2272, a direct activator of soluble guanylate cyclase, reduces right ventricular hypertrophy and prevents pulmonary vascular remodeling during chronic hypoxia in neonatal rats. [electronic resource] - Biology of the neonate 2006 - 135-44 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

0006-3126

10.1159/000092518 doi


Animals
Animals, Newborn
Chronic Disease
Enzyme Activation--drug effects
Female
Guanylate Cyclase--metabolism
Hypertension, Pulmonary--drug therapy
Hypertrophy, Right Ventricular--pathology
Hypoxia--complications
Lung--blood supply
Organ Size
Pregnancy
Pulmonary Artery--drug effects
Pyrazoles--pharmacology
Pyridines--pharmacology
Rats
Rats, Sprague-Dawley
Vasodilation--drug effects