Glutamic acid 709 substitutions highlight the importance of the interaction between androgen receptor helices H3 and H12 for androgen and antiandrogen actions. [electronic resource]
Producer: 20060623Description: 724-34 p. digitalISSN:- 0888-8809
- Amino Acid Substitution
- Androgen Antagonists -- pharmacology
- Androgen-Insensitivity Syndrome -- genetics
- Androgens -- pharmacology
- Animals
- Base Sequence
- Cell Line
- Cyproterone Acetate -- pharmacology
- DNA, Complementary -- genetics
- Humans
- In Vitro Techniques
- Infant
- Male
- Models, Molecular
- Mutagenesis, Site-Directed
- Mutation
- Protein Conformation
- Protein Structure, Secondary
- Receptors, Androgen -- chemistry
- Recombinant Proteins -- chemistry
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Publication Type: Case Reports; Journal Article
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