Glutamic acid 709 substitutions highlight the importance of the interaction between androgen receptor helices H3 and H12 for androgen and antiandrogen actions.

Georget, Virginie

Glutamic acid 709 substitutions highlight the importance of the interaction between androgen receptor helices H3 and H12 for androgen and antiandrogen actions. [electronic resource] - Molecular endocrinology (Baltimore, Md.) Apr 2006 - 724-34 p. digital

Publication Type: Case Reports; Journal Article

0888-8809

10.1210/me.2005-0419 doi


Amino Acid Substitution
Androgen Antagonists--pharmacology
Androgen-Insensitivity Syndrome--genetics
Androgens--pharmacology
Animals
Base Sequence
Cell Line
Cyproterone Acetate--pharmacology
DNA, Complementary--genetics
Humans
In Vitro Techniques
Infant
Male
Models, Molecular
Mutagenesis, Site-Directed
Mutation
Protein Conformation
Protein Structure, Secondary
Receptors, Androgen--chemistry
Recombinant Proteins--chemistry