Discovery of indoles as potent and selective inhibitors of the deacetylase SIRT1. [electronic resource]
Producer: 20060207Description: 8045-54 p. digitalISSN:- 0022-2623
- Animals
- Biological Availability
- CHO Cells
- Carbazoles -- chemical synthesis
- Cell Membrane Permeability
- Cricetinae
- Cricetulus
- Drug Stability
- Fluorometry
- Histone Deacetylase Inhibitors
- Histone Deacetylases -- chemistry
- Humans
- In Vitro Techniques
- Indoles -- chemical synthesis
- Kinetics
- Mice
- Mice, Inbred C57BL
- Microsomes, Liver -- metabolism
- NAD -- chemistry
- NAD+ Nucleosidase -- chemistry
- Niacinamide -- chemistry
- Rats
- Recombinant Proteins -- antagonists & inhibitors
- Sirtuin 1
- Sirtuins -- antagonists & inhibitors
- Stereoisomerism
- Structure-Activity Relationship
No physical items for this record
Publication Type: Journal Article
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