Lysosomotropism of basic cathepsin K inhibitors contributes to increased cellular potencies against off-target cathepsins and reduced functional selectivity. [electronic resource]
Producer: 20060209Description: 7535-43 p. digitalISSN:- 0022-2623
- Animals
- Antigen Presentation -- drug effects
- Autoradiography
- Benzamides -- chemistry
- Bone Density Conservation Agents -- chemistry
- Cathepsin B -- antagonists & inhibitors
- Cathepsin K
- Cathepsin L
- Cathepsins -- antagonists & inhibitors
- Cell Line
- Cysteine Endopeptidases
- Female
- Humans
- Lysosomes -- drug effects
- Mice
- Mice, Inbred C57BL
- Morpholines -- chemistry
- Piperazines -- chemistry
- Rabbits
- Rats
- Structure-Activity Relationship
- Thiazoles -- chemistry
- Tissue Distribution
No physical items for this record
Publication Type: Journal Article
There are no comments on this title.
Log in to your account to post a comment.