Beta-amyloid-stimulated microglia induce neuron death via synergistic stimulation of tumor necrosis factor alpha and NMDA receptors. [electronic resource]
Producer: 20060302Description: 2566-75 p. digitalISSN:- 1529-2401
- Amyloid beta-Peptides -- pharmacology
- Animals
- Cell Death -- drug effects
- Cells, Cultured
- Cerebral Cortex -- drug effects
- Culture Media, Conditioned -- pharmacology
- Dose-Response Relationship, Drug
- Drug Synergism
- Female
- Glutamic Acid -- metabolism
- Humans
- Mice
- Mice, Inbred C57BL
- Microglia -- drug effects
- Neurons -- drug effects
- Pregnancy
- Receptors, N-Methyl-D-Aspartate -- agonists
- Tumor Necrosis Factor-alpha -- agonists
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Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.
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