Beta-amyloid-stimulated microglia induce neuron death via synergistic stimulation of tumor necrosis factor alpha and NMDA receptors.
Floden, Angela M
Beta-amyloid-stimulated microglia induce neuron death via synergistic stimulation of tumor necrosis factor alpha and NMDA receptors. [electronic resource] - The Journal of neuroscience : the official journal of the Society for Neuroscience Mar 2005 - 2566-75 p. digital
Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.
1529-2401
10.1523/JNEUROSCI.4998-04.2005 doi
Amyloid beta-Peptides--pharmacology
Animals
Cell Death--drug effects
Cells, Cultured
Cerebral Cortex--drug effects
Culture Media, Conditioned--pharmacology
Dose-Response Relationship, Drug
Drug Synergism
Female
Glutamic Acid--metabolism
Humans
Mice
Mice, Inbred C57BL
Microglia--drug effects
Neurons--drug effects
Pregnancy
Receptors, N-Methyl-D-Aspartate--agonists
Tumor Necrosis Factor-alpha--agonists
Beta-amyloid-stimulated microglia induce neuron death via synergistic stimulation of tumor necrosis factor alpha and NMDA receptors. [electronic resource] - The Journal of neuroscience : the official journal of the Society for Neuroscience Mar 2005 - 2566-75 p. digital
Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.
1529-2401
10.1523/JNEUROSCI.4998-04.2005 doi
Amyloid beta-Peptides--pharmacology
Animals
Cell Death--drug effects
Cells, Cultured
Cerebral Cortex--drug effects
Culture Media, Conditioned--pharmacology
Dose-Response Relationship, Drug
Drug Synergism
Female
Glutamic Acid--metabolism
Humans
Mice
Mice, Inbred C57BL
Microglia--drug effects
Neurons--drug effects
Pregnancy
Receptors, N-Methyl-D-Aspartate--agonists
Tumor Necrosis Factor-alpha--agonists