In vivo efficacy of HSV-TK transcriptionally targeted to the tumour vasculature is augmented by combination with cytotoxic chemotherapy. [electronic resource]
Producer: 20051128Description: 263-75 p. digitalISSN:- 1099-498X
- Animals
- Antineoplastic Agents, Phytogenic -- therapeutic use
- Aorta -- cytology
- Camptothecin -- analogs & derivatives
- Cell Line, Tumor
- Cisplatin -- therapeutic use
- Drug Therapy, Combination
- Endothelial Cells -- cytology
- Genes, Reporter
- Genetic Therapy -- methods
- Genetic Vectors -- genetics
- Humans
- Irinotecan
- Neoplasms -- blood supply
- Retroviridae -- genetics
- Simplexvirus -- enzymology
- Survival Rate
- Swine
- Thymidine Kinase -- genetics
- Transcription, Genetic
- Treatment Outcome
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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