In vivo efficacy of HSV-TK transcriptionally targeted to the tumour vasculature is augmented by combination with cytotoxic chemotherapy.

Mavria, Georgia

In vivo efficacy of HSV-TK transcriptionally targeted to the tumour vasculature is augmented by combination with cytotoxic chemotherapy. [electronic resource] - The journal of gene medicine Mar 2005 - 263-75 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1099-498X

10.1002/jgm.662 doi


Animals
Antineoplastic Agents, Phytogenic--therapeutic use
Aorta--cytology
Camptothecin--analogs & derivatives
Cell Line, Tumor
Cisplatin--therapeutic use
Drug Therapy, Combination
Endothelial Cells--cytology
Genes, Reporter
Genetic Therapy--methods
Genetic Vectors--genetics
Humans
Irinotecan
Neoplasms--blood supply
Retroviridae--genetics
Simplexvirus--enzymology
Survival Rate
Swine
Thymidine Kinase--genetics
Transcription, Genetic
Treatment Outcome