Olanzapine produces trophic effects in vitro and stimulates phosphorylation of Akt/PKB, ERK1/2, and the mitogen-activated protein kinase p38. [electronic resource]
Producer: 20040823Description: 58-68 p. digitalISSN:- 0006-8993
- 3-Phosphoinositide-Dependent Protein Kinases
- Amyloid beta-Peptides -- pharmacology
- Animals
- Antipsychotic Agents -- pharmacology
- Benzodiazepines -- pharmacology
- Blotting, Western -- methods
- Bromodeoxyuridine -- metabolism
- Cell Division -- drug effects
- Cells, Cultured
- Cerebral Cortex -- cytology
- Culture Media, Serum-Free -- pharmacology
- Dose-Response Relationship, Drug
- Drug Interactions
- Enzyme Activation -- drug effects
- Enzyme Inhibitors -- pharmacology
- Humans
- Mice
- Mitogen-Activated Protein Kinase 1 -- metabolism
- Mitogen-Activated Protein Kinase 3
- Mitogen-Activated Protein Kinases -- metabolism
- Neuroblastoma
- Neurons -- drug effects
- Olanzapine
- Peptide Fragments -- pharmacology
- Pertussis Toxin -- pharmacology
- Phosphorylation -- drug effects
- Protein Serine-Threonine Kinases -- metabolism
- Rats
- Tetrazolium Salts
- Thiazoles
- Time Factors
- p38 Mitogen-Activated Protein Kinases
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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