Expression of the human CYP3A4 gene in the small intestine of transgenic mice: in vitro metabolism and pharmacokinetics of midazolam. [electronic resource]
Producer: 20031210Description: 548-58 p. digitalISSN:- 0090-9556
- Administration, Oral
- Animals
- Area Under Curve
- Biological Availability
- Blotting, Southern
- Cytochrome P-450 CYP3A
- Cytochrome P-450 Enzyme System -- genetics
- Dexamethasone -- pharmacology
- Drug Interactions
- Enzyme Inhibitors -- pharmacology
- Half-Life
- Humans
- In Vitro Techniques
- Intestine, Small -- metabolism
- Ketoconazole -- pharmacology
- Male
- Mice
- Mice, Transgenic
- Microsomes -- drug effects
- Midazolam -- analogs & derivatives
- Polymerase Chain Reaction
- Rifampin -- pharmacology
- Time Factors
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Publication Type: Journal Article
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