Rac affects invasion of human renal cell carcinomas by up-regulating tissue inhibitor of metalloproteinases (TIMP)-1 and TIMP-2 expression. [electronic resource]
Producer: 20011205Description: 41889-97 p. digitalISSN:- 0021-9258
- Carcinoma, Renal Cell -- pathology
- Cell Adhesion
- Cell Movement
- Gene Expression Regulation, Neoplastic
- Guanine Nucleotide Exchange Factors
- Humans
- Kidney Neoplasms -- pathology
- Matrix Metalloproteinase 2 -- genetics
- Neoplasm Invasiveness
- Promoter Regions, Genetic
- Proteins -- physiology
- T-Lymphoma Invasion and Metastasis-inducing Protein 1
- Tissue Inhibitor of Metalloproteinase-1 -- genetics
- Tissue Inhibitor of Metalloproteinase-2 -- genetics
- Tumor Cells, Cultured
- Up-Regulation
- rac GTP-Binding Proteins -- physiology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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