Rac affects invasion of human renal cell carcinomas by up-regulating tissue inhibitor of metalloproteinases (TIMP)-1 and TIMP-2 expression.

Engers, R

Rac affects invasion of human renal cell carcinomas by up-regulating tissue inhibitor of metalloproteinases (TIMP)-1 and TIMP-2 expression. [electronic resource] - The Journal of biological chemistry Nov 2001 - 41889-97 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0021-9258

10.1074/jbc.M105049200 doi


Carcinoma, Renal Cell--pathology
Cell Adhesion
Cell Movement
Gene Expression Regulation, Neoplastic
Guanine Nucleotide Exchange Factors
Humans
Kidney Neoplasms--pathology
Matrix Metalloproteinase 2--genetics
Neoplasm Invasiveness
Promoter Regions, Genetic
Proteins--physiology
T-Lymphoma Invasion and Metastasis-inducing Protein 1
Tissue Inhibitor of Metalloproteinase-1--genetics
Tissue Inhibitor of Metalloproteinase-2--genetics
Tumor Cells, Cultured
Up-Regulation
rac GTP-Binding Proteins--physiology