Systemic IFN-beta gene therapy results in long-term survival in mice with established colorectal liver metastases. [electronic resource]
Producer: 20010809Description: 83-95 p. digitalISSN:- 0021-9738
- Adenocarcinoma -- drug therapy
- Adenoviridae -- genetics
- Animals
- Apoptosis
- Colorectal Neoplasms -- pathology
- Cytomegalovirus -- genetics
- DNA, Complementary -- administration & dosage
- Female
- Genes, Synthetic
- Genetic Therapy
- Genetic Vectors -- administration & dosage
- Hepatocytes -- metabolism
- Humans
- Injections, Intraperitoneal
- Injections, Intravenous
- Interferon-beta -- administration & dosage
- Killer Cells, Natural -- drug effects
- Liver Neoplasms -- drug therapy
- Macrophages -- drug effects
- Mice
- Mice, Inbred BALB C
- Mice, Nude
- Mice, SCID
- Neoplasm Transplantation
- Neovascularization, Pathologic -- drug therapy
- Promoter Regions, Genetic
- Recombinant Fusion Proteins -- administration & dosage
- Tumor Cells, Cultured -- transplantation
- Xenograft Model Antitumor Assays
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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