Receptor-mediated inhibition of G protein-coupled inwardly rectifying potassium channels involves G(alpha)q family subunits, phospholipase C, and a readily diffusible messenger. [electronic resource]
Producer: 20010705Description: 16720-30 p. digitalISSN:- 0021-9258
- Bacterial Proteins
- Bacterial Toxins -- pharmacology
- Cell Line
- Cell Membrane -- physiology
- Dimerization
- Enzyme Inhibitors -- pharmacology
- Estrenes -- pharmacology
- G Protein-Coupled Inwardly-Rectifying Potassium Channels
- GTP-Binding Protein alpha Subunits, Gq-G11
- Heterotrimeric GTP-Binding Proteins -- chemistry
- Humans
- Indoles -- pharmacology
- Inositol 1,4,5-Trisphosphate -- metabolism
- Maleimides -- pharmacology
- Membrane Potentials -- drug effects
- Pasteurella multocida
- Phorbol Esters -- pharmacology
- Potassium Channel Blockers
- Potassium Channels -- physiology
- Potassium Channels, Inwardly Rectifying
- Protein Subunits
- Pyrrolidinones -- pharmacology
- Receptors, Serotonin -- drug effects
- Receptors, Serotonin, 5-HT1
- Receptors, Thyrotropin-Releasing Hormone -- drug effects
- Recombinant Proteins -- metabolism
- Serotonin -- pharmacology
- Thyrotropin-Releasing Hormone -- pharmacology
- Transfection
- Type C Phospholipases -- metabolism
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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