Receptor-mediated inhibition of G protein-coupled inwardly rectifying potassium channels involves G(alpha)q family subunits, phospholipase C, and a readily diffusible messenger.

Lei, Q

Receptor-mediated inhibition of G protein-coupled inwardly rectifying potassium channels involves G(alpha)q family subunits, phospholipase C, and a readily diffusible messenger. [electronic resource] - The Journal of biological chemistry May 2001 - 16720-30 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

0021-9258

10.1074/jbc.M100207200 doi


Bacterial Proteins
Bacterial Toxins--pharmacology
Cell Line
Cell Membrane--physiology
Dimerization
Enzyme Inhibitors--pharmacology
Estrenes--pharmacology
G Protein-Coupled Inwardly-Rectifying Potassium Channels
GTP-Binding Protein alpha Subunits, Gq-G11
Heterotrimeric GTP-Binding Proteins--chemistry
Humans
Indoles--pharmacology
Inositol 1,4,5-Trisphosphate--metabolism
Maleimides--pharmacology
Membrane Potentials--drug effects
Pasteurella multocida
Phorbol Esters--pharmacology
Potassium Channel Blockers
Potassium Channels--physiology
Potassium Channels, Inwardly Rectifying
Protein Subunits
Pyrrolidinones--pharmacology
Receptors, Serotonin--drug effects
Receptors, Serotonin, 5-HT1
Receptors, Thyrotropin-Releasing Hormone--drug effects
Recombinant Proteins--metabolism
Serotonin--pharmacology
Thyrotropin-Releasing Hormone--pharmacology
Transfection
Type C Phospholipases--metabolism