Retrovirus-mediated gene transfer in primary T lymphocytes: influence of the transduction/selection process and of ex vivo expansion on the T cell receptor beta chain hypervariable region repertoire. [electronic resource]
Producer: 20000914Description: 1151-64 p. digitalISSN:- 1043-0342
- CD28 Antigens -- metabolism
- CD4-Positive T-Lymphocytes -- metabolism
- CD8-Positive T-Lymphocytes -- metabolism
- Cell Line
- DNA, Complementary -- metabolism
- Gene Transfer Techniques
- Genes, T-Cell Receptor beta -- genetics
- Humans
- Immunoglobulin Variable Region -- genetics
- Immunosuppressive Agents -- pharmacology
- Interleukin-2 -- pharmacology
- Kinetics
- Leukocytes, Mononuclear -- metabolism
- Muromonab-CD3 -- pharmacology
- Oligonucleotides -- metabolism
- RNA -- metabolism
- Retroviridae -- genetics
- Reverse Transcriptase Polymerase Chain Reaction
- T-Lymphocytes -- metabolism
- Time Factors
- Transduction, Genetic
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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