Dexamethasone makes the gastric mucosa susceptible to ulceration by inhibiting prostaglandin synthetase and peroxidase--two important gastroprotective enzymes. [electronic resource]
Producer: 20000411Description: 31-6 p. digitalISSN:- 0300-8177
- Animals
- Cimetidine -- pharmacology
- Cyclooxygenase Inhibitors -- pharmacology
- Dexamethasone -- pharmacology
- Gastric Acid -- metabolism
- Gastric Mucosa -- drug effects
- Histamine Release -- drug effects
- Imidazoles -- pharmacology
- Male
- Pepsin A -- analysis
- Peroxidases -- antagonists & inhibitors
- Prostaglandin-Endoperoxide Synthases -- metabolism
- Rats
- Rats, Wistar
- Stomach Ulcer -- etiology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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