Isomers of substituted 3-benzo[b]furyl and 3-thienylaminobutyric acids as potent ligands of the GABA-B receptor: synthesis and preparative liquid chromatographic separation. [electronic resource]
Producer: 20000316Description: 651-8 p. digitalISSN:- 0040-5957
- Aminobutyrates -- chemical synthesis
- Animals
- Baclofen -- metabolism
- Binding, Competitive
- Drug Design
- GABA Agonists -- chemical synthesis
- GABA Antagonists -- chemical synthesis
- Ligands
- Male
- Molecular Structure
- Muscimol -- metabolism
- Nerve Tissue Proteins -- drug effects
- Protein Binding
- Rats
- Rats, Wistar
- Receptors, GABA-B -- drug effects
- Stereoisomerism
- Structure-Activity Relationship
- gamma-Aminobutyric Acid -- metabolism
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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