Isomers of substituted 3-benzo[b]furyl and 3-thienylaminobutyric acids as potent ligands of the GABA-B receptor: synthesis and preparative liquid chromatographic separation.
Ansar, M
Isomers of substituted 3-benzo[b]furyl and 3-thienylaminobutyric acids as potent ligands of the GABA-B receptor: synthesis and preparative liquid chromatographic separation. [electronic resource] - Therapie - 651-8 p. digital
Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
0040-5957
Aminobutyrates--chemical synthesis
Animals
Baclofen--metabolism
Binding, Competitive
Drug Design
GABA Agonists--chemical synthesis
GABA Antagonists--chemical synthesis
Ligands
Male
Molecular Structure
Muscimol--metabolism
Nerve Tissue Proteins--drug effects
Protein Binding
Rats
Rats, Wistar
Receptors, GABA-B--drug effects
Stereoisomerism
Structure-Activity Relationship
gamma-Aminobutyric Acid--metabolism
Isomers of substituted 3-benzo[b]furyl and 3-thienylaminobutyric acids as potent ligands of the GABA-B receptor: synthesis and preparative liquid chromatographic separation. [electronic resource] - Therapie - 651-8 p. digital
Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
0040-5957
Aminobutyrates--chemical synthesis
Animals
Baclofen--metabolism
Binding, Competitive
Drug Design
GABA Agonists--chemical synthesis
GABA Antagonists--chemical synthesis
Ligands
Male
Molecular Structure
Muscimol--metabolism
Nerve Tissue Proteins--drug effects
Protein Binding
Rats
Rats, Wistar
Receptors, GABA-B--drug effects
Stereoisomerism
Structure-Activity Relationship
gamma-Aminobutyric Acid--metabolism