E1B 55-kilodalton oncoproteins of adenovirus types 5 and 12 inactivate and relocalize p53, but not p51 or p73, and cooperate with E4orf6 proteins to destabilize p53. [electronic resource]
Producer: 20000110Description: 193-202 p. digitalISSN:- 0022-538X
- Adenovirus E1B Proteins -- physiology
- Base Sequence
- Cell Nucleus -- metabolism
- Cytoplasm -- metabolism
- DNA Primers
- DNA-Binding Proteins -- metabolism
- Genes, Tumor Suppressor
- Humans
- Nuclear Proteins -- metabolism
- Open Reading Frames
- Phosphoproteins
- Trans-Activators
- Transcription Factors
- Transcription, Genetic
- Tumor Protein p73
- Tumor Suppressor Protein p53 -- antagonists & inhibitors
- Tumor Suppressor Proteins
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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