E1B 55-kilodalton oncoproteins of adenovirus types 5 and 12 inactivate and relocalize p53, but not p51 or p73, and cooperate with E4orf6 proteins to destabilize p53.

Wienzek, S

E1B 55-kilodalton oncoproteins of adenovirus types 5 and 12 inactivate and relocalize p53, but not p51 or p73, and cooperate with E4orf6 proteins to destabilize p53. [electronic resource] - Journal of virology Jan 2000 - 193-202 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0022-538X

10.1128/jvi.74.1.193-202.2000 doi


Adenovirus E1B Proteins--physiology
Base Sequence
Cell Nucleus--metabolism
Cytoplasm--metabolism
DNA Primers
DNA-Binding Proteins--metabolism
Genes, Tumor Suppressor
Humans
Nuclear Proteins--metabolism
Open Reading Frames
Phosphoproteins
Trans-Activators
Transcription Factors
Transcription, Genetic
Tumor Protein p73
Tumor Suppressor Protein p53--antagonists & inhibitors
Tumor Suppressor Proteins