Antiangiogenic therapy targeting the tyrosine kinase receptor for vascular endothelial growth factor receptor inhibits the growth of colon cancer liver metastasis and induces tumor and endothelial cell apoptosis. [electronic resource]
Producer: 19991202Description: 5412-6 p. digitalISSN:- 0008-5472
- Animals
- Apoptosis
- Colonic Neoplasms -- drug therapy
- Endothelium -- drug effects
- Fluorescent Antibody Technique
- In Situ Nick-End Labeling
- Indoles -- pharmacology
- Liver Neoplasms -- drug therapy
- Male
- Mice
- Mice, Inbred BALB C
- Neovascularization, Pathologic -- drug therapy
- Pyrroles -- pharmacology
- Random Allocation
- Receptor Protein-Tyrosine Kinases -- drug effects
- Receptors, Growth Factor -- drug effects
- Receptors, Vascular Endothelial Growth Factor
- Tumor Cells, Cultured
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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