000 02662 a2200649 4500
005 20250513163713.0
264 0 _c19990413
008 199904s 0 0 eng d
022 _a0022-1767
040 _aNLM
_beng
_cNLM
100 1 _aManna, S K
245 0 0 _aImmunosuppressive leflunomide metabolite (A77 1726) blocks TNF-dependent nuclear factor-kappa B activation and gene expression.
_h[electronic resource]
260 _bJournal of immunology (Baltimore, Md. : 1950)
_cFeb 1999
300 _a2095-102 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAniline Compounds
_xantagonists & inhibitors
650 0 4 _aBiological Transport
_xdrug effects
650 0 4 _aCell Nucleus
_xdrug effects
650 0 4 _aCeramides
_xantagonists & inhibitors
650 0 4 _aChloramphenicol O-Acetyltransferase
_xantagonists & inhibitors
650 0 4 _aCrotonates
650 0 4 _aDNA-Binding Proteins
_xantagonists & inhibitors
650 0 4 _aDithiothreitol
_xpharmacology
650 0 4 _aEnzyme Activation
_xdrug effects
650 0 4 _aGene Expression Regulation
_xdrug effects
650 0 4 _aGenes, MDR
_xdrug effects
650 0 4 _aGenes, Reporter
_xdrug effects
650 0 4 _aHost Cell Factor C1
650 0 4 _aHumans
650 0 4 _aHydrogen Peroxide
_xantagonists & inhibitors
650 0 4 _aHydroxybutyrates
_xantagonists & inhibitors
650 0 4 _aI-kappa B Proteins
650 0 4 _aImmunosuppressive Agents
_xantagonists & inhibitors
650 0 4 _aIsoxazoles
_xantagonists & inhibitors
650 0 4 _aLeflunomide
650 0 4 _aLipopolysaccharides
_xantagonists & inhibitors
650 0 4 _aLymphocyte Specific Protein Tyrosine Kinase p56(lck)
_xantagonists & inhibitors
650 0 4 _aMitogen-Activated Protein Kinase Kinases
650 0 4 _aNF-KappaB Inhibitor alpha
650 0 4 _aNF-kappa B
_xantagonists & inhibitors
650 0 4 _aNF-kappa B p50 Subunit
650 0 4 _aNitriles
650 0 4 _aOctamer Transcription Factor-1
650 0 4 _aOkadaic Acid
_xantagonists & inhibitors
650 0 4 _aProtein Binding
_xdrug effects
650 0 4 _aProtein Kinase Inhibitors
650 0 4 _aProtein Kinases
_xmetabolism
650 0 4 _aTetradecanoylphorbol Acetate
_xantagonists & inhibitors
650 0 4 _aToluidines
650 0 4 _aTranscription Factor AP-1
_xmetabolism
650 0 4 _aTranscription Factor RelA
650 0 4 _aTranscription Factors
_xmetabolism
650 0 4 _aTumor Cells, Cultured
650 0 4 _aTumor Necrosis Factor-alpha
_xantagonists & inhibitors
700 1 _aAggarwal, B B
773 0 _tJournal of immunology (Baltimore, Md. : 1950)
_gvol. 162
_gno. 4
_gp. 2095-102
999 _c9935039
_d9935039