000 01299 a2200325 4500
005 20250513160552.0
264 0 _c19990126
008 199901s 0 0 eng d
022 _a0960-894X
024 7 _a10.1016/s0960-894x(98)00553-8
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aGraziani, E I
245 0 0 _aMacrolide biosynthesis: a single cytochrome P450, PicK, is responsible for the hydroxylations that generate methymycin, neomethymycin, and picromycin in Streptomyces venezuelae.
_h[electronic resource]
260 _bBioorganic & medicinal chemistry letters
_cNov 1998
300 _a3117-20 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
650 0 4 _aAnti-Bacterial Agents
_xbiosynthesis
650 0 4 _aBacterial Proteins
650 0 4 _aCytochrome P-450 Enzyme System
_xgenetics
650 0 4 _aHydroxylation
650 0 4 _aMacrolides
650 0 4 _aMixed Function Oxygenases
_xgenetics
650 0 4 _aStreptomyces
_xmetabolism
700 1 _aCane, D E
700 1 _aBetlach, M C
700 1 _aKealey, J T
700 1 _aMcDaniel, R
773 0 _tBioorganic & medicinal chemistry letters
_gvol. 8
_gno. 22
_gp. 3117-20
856 4 0 _uhttps://doi.org/10.1016/s0960-894x(98)00553-8
_zAvailable from publisher's website
999 _c9836106
_d9836106