000 01279 a2200337 4500
005 20250513160514.0
264 0 _c19990204
008 199902s 0 0 eng d
022 _a0960-894X
024 7 _a10.1016/s0960-894x(98)00036-5
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aHulme, C
245 0 0 _aQuaternary substituted PDE IV inhibitors II: the synthesis and in vitro evaluation of a novel series of gamma-lactams.
_h[electronic resource]
260 _bBioorganic & medicinal chemistry letters
_cFeb 1998
300 _a399-404 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _a3',5'-Cyclic-AMP Phosphodiesterases
_xantagonists & inhibitors
650 0 4 _aCyclic Nucleotide Phosphodiesterases, Type 4
650 0 4 _aLactams
_xchemical synthesis
650 0 4 _aPhosphodiesterase Inhibitors
_xchemical synthesis
650 0 4 _aStructure-Activity Relationship
700 1 _aMoriarty, K
700 1 _aHuang, F C
700 1 _aMason, J
700 1 _aMcGarry, D
700 1 _aLabaudiniere, R
700 1 _aSouness, J
700 1 _aDjuric, S
773 0 _tBioorganic & medicinal chemistry letters
_gvol. 8
_gno. 4
_gp. 399-404
856 4 0 _uhttps://doi.org/10.1016/s0960-894x(98)00036-5
_zAvailable from publisher's website
999 _c9834117
_d9834117