000 01569 a2200445 4500
005 20250513155305.0
264 0 _c19990105
008 199901s 0 0 eng d
022 _a0006-4971
040 _aNLM
_beng
_cNLM
100 1 _aMaran, A
245 0 0 _a2',5'-Oligoadenylate-antisense chimeras cause RNase L to selectively degrade bcr/abl mRNA in chronic myelogenous leukemia cells.
_h[electronic resource]
260 _bBlood
_cDec 1998
300 _a4336-43 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
650 0 4 _aAdenine Nucleotides
_xgenetics
650 0 4 _aEndoribonucleases
_xgenetics
650 0 4 _aEnzyme Activation
_xgenetics
650 0 4 _aFusion Proteins, bcr-abl
_xantagonists & inhibitors
650 0 4 _aGene Expression Regulation, Neoplastic
650 0 4 _aHumans
650 0 4 _aLeukemia, Myelogenous, Chronic, BCR-ABL Positive
_xdrug therapy
650 0 4 _aOligonucleotides, Antisense
_xgenetics
650 0 4 _aOligoribonucleotides
_xgenetics
650 0 4 _aRNA, Messenger
_xantagonists & inhibitors
650 0 4 _aRecombinant Fusion Proteins
_xgenetics
650 0 4 _aTumor Cells, Cultured
700 1 _aWaller, C F
700 1 _aParanjape, J M
700 1 _aLi, G
700 1 _aXiao, W
700 1 _aZhang, K
700 1 _aKalaycio, M E
700 1 _aMaitra, R K
700 1 _aLichtin, A E
700 1 _aBrugger, W
700 1 _aTorrence, P F
700 1 _aSilverman, R H
773 0 _tBlood
_gvol. 92
_gno. 11
_gp. 4336-43
999 _c9798319
_d9798319