000 01680 a2200517 4500
005 20250513154840.0
264 0 _c19990126
008 199901s 0 0 eng d
022 _a0264-6021
024 7 _a10.1042/bj3360299
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aBruneau, J M
245 0 0 _aPurification of human dihydro-orotate dehydrogenase and its inhibition by A77 1726, the active metabolite of leflunomide.
_h[electronic resource]
260 _bThe Biochemical journal
_cDec 1998
300 _a299-303 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aAniline Compounds
_xmetabolism
650 0 4 _aBinding Sites
650 0 4 _aBinding, Competitive
650 0 4 _aCell Division
_xdrug effects
650 0 4 _aCell Membrane
_xdrug effects
650 0 4 _aCrotonates
650 0 4 _aDihydroorotate Dehydrogenase
650 0 4 _aHumans
650 0 4 _aHydroxybutyrates
_xmetabolism
650 0 4 _aLymphoma
_xenzymology
650 0 4 _aNitriles
650 0 4 _aOxidoreductases
_xantagonists & inhibitors
650 0 4 _aOxidoreductases Acting on CH-CH Group Donors
650 0 4 _aSpleen
_xenzymology
650 0 4 _aToluidines
650 0 4 _aTumor Cells, Cultured
650 0 4 _aUridine
_xmetabolism
700 1 _aYea, C M
700 1 _aSpinella-Jaegle, S
700 1 _aFudali, C
700 1 _aWoodward, K
700 1 _aRobson, P A
700 1 _aSautès, C
700 1 _aWestwood, R
700 1 _aKuo, E A
700 1 _aWilliamson, R A
700 1 _aRuuth, E
773 0 _tThe Biochemical journal
_gvol. 336 ( Pt 2)
_gp. 299-303
856 4 0 _uhttps://doi.org/10.1042/bj3360299
_zAvailable from publisher's website
999 _c9784998
_d9784998