000 01801 a2200553 4500
005 20250513152346.0
264 0 _c19981019
008 199810s 0 0 eng d
022 _a0022-2623
024 7 _a10.1021/jm9800806
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aNugent, R A
245 0 0 _aPyrimidine thioethers: a novel class of HIV-1 reverse transcriptase inhibitors with activity against BHAP-resistant HIV.
_h[electronic resource]
260 _bJournal of medicinal chemistry
_cSep 1998
300 _a3793-803 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aAmino Acid Substitution
650 0 4 _aAnimals
650 0 4 _aAnti-HIV Agents
_xchemical synthesis
650 0 4 _aCell Line
650 0 4 _aDelavirdine
_xpharmacology
650 0 4 _aDrug Resistance, Microbial
650 0 4 _aHIV Reverse Transcriptase
_xantagonists & inhibitors
650 0 4 _aHIV-1
_xdrug effects
650 0 4 _aLeucine
_xgenetics
650 0 4 _aMice
650 0 4 _aProline
_xgenetics
650 0 4 _aPyrimidines
_xchemical synthesis
650 0 4 _aReverse Transcriptase Inhibitors
_xchemical synthesis
650 0 4 _aStructure-Activity Relationship
650 0 4 _aSulfides
_xchemical synthesis
700 1 _aSchlachter, S T
700 1 _aMurphy, M J
700 1 _aCleek, G J
700 1 _aPoel, T J
700 1 _aWishka, D G
700 1 _aGraber, D R
700 1 _aYagi, Y
700 1 _aKeiser, B J
700 1 _aOlmsted, R A
700 1 _aKopta, L A
700 1 _aSwaney, S M
700 1 _aPoppe, S M
700 1 _aMorris, J
700 1 _aTarpley, W G
700 1 _aThomas, R C
773 0 _tJournal of medicinal chemistry
_gvol. 41
_gno. 20
_gp. 3793-803
856 4 0 _uhttps://doi.org/10.1021/jm9800806
_zAvailable from publisher's website
999 _c9713331
_d9713331