| 000 | 02397 a2200757 4500 | ||
|---|---|---|---|
| 005 | 20250513150822.0 | ||
| 264 | 0 | _c19980909 | |
| 008 | 199809s 0 0 eng d | ||
| 022 | _a0022-2623 | ||
| 024 | 7 |
_a10.1021/jm9802259 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aKlutchko, S R | |
| 245 | 0 | 0 |
_a2-Substituted aminopyrido[2,3-d]pyrimidin-7(8H)-ones. structure-activity relationships against selected tyrosine kinases and in vitro and in vivo anticancer activity. _h[electronic resource] |
| 260 |
_bJournal of medicinal chemistry _cAug 1998 |
||
| 300 |
_a3276-92 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article | ||
| 650 | 0 | 4 | _a3T3 Cells |
| 650 | 0 | 4 | _aAnimals |
| 650 | 0 | 4 |
_aAntineoplastic Agents _xchemical synthesis |
| 650 | 0 | 4 | _aBiotransformation |
| 650 | 0 | 4 |
_aCell Division _xdrug effects |
| 650 | 0 | 4 |
_aCisplatin _xtherapeutic use |
| 650 | 0 | 4 |
_aEnzyme Inhibitors _xchemical synthesis |
| 650 | 0 | 4 | _aFemale |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 | _aMale |
| 650 | 0 | 4 | _aMice |
| 650 | 0 | 4 | _aMice, Nude |
| 650 | 0 | 4 | _aMolecular Conformation |
| 650 | 0 | 4 | _aMolecular Structure |
| 650 | 0 | 4 |
_aOvarian Neoplasms _xdrug therapy |
| 650 | 0 | 4 |
_aPlatelet-Derived Growth Factor _xpharmacology |
| 650 | 0 | 4 |
_aProtein-Tyrosine Kinases _xantagonists & inhibitors |
| 650 | 0 | 4 |
_aPyrimidinones _xchemical synthesis |
| 650 | 0 | 4 | _aRats |
| 650 | 0 | 4 |
_aReceptor Protein-Tyrosine Kinases _xantagonists & inhibitors |
| 650 | 0 | 4 | _aStructure-Activity Relationship |
| 650 | 0 | 4 | _aTransplantation, Heterologous |
| 650 | 0 | 4 | _aTumor Cells, Cultured |
| 700 | 1 | _aHamby, J M | |
| 700 | 1 | _aBoschelli, D H | |
| 700 | 1 | _aWu, Z | |
| 700 | 1 | _aKraker, A J | |
| 700 | 1 | _aAmar, A M | |
| 700 | 1 | _aHartl, B G | |
| 700 | 1 | _aShen, C | |
| 700 | 1 | _aKlohs, W D | |
| 700 | 1 | _aSteinkampf, R W | |
| 700 | 1 | _aDriscoll, D L | |
| 700 | 1 | _aNelson, J M | |
| 700 | 1 | _aElliott, W L | |
| 700 | 1 | _aRoberts, B J | |
| 700 | 1 | _aStoner, C L | |
| 700 | 1 | _aVincent, P W | |
| 700 | 1 | _aDykes, D J | |
| 700 | 1 | _aPanek, R L | |
| 700 | 1 | _aLu, G H | |
| 700 | 1 | _aMajor, T C | |
| 700 | 1 | _aDahring, T K | |
| 700 | 1 | _aHallak, H | |
| 700 | 1 | _aBradford, L A | |
| 700 | 1 | _aShowalter, H D | |
| 700 | 1 | _aDoherty, A M | |
| 773 | 0 |
_tJournal of medicinal chemistry _gvol. 41 _gno. 17 _gp. 3276-92 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1021/jm9802259 _zAvailable from publisher's website |
| 999 |
_c9669080 _d9669080 |
||