000			01783 a2200505 4500
005			20250513150822.0
264		0	_c19980909
008			199809s 0 0 eng d
022			_a0022-2623
024	7		_a10.1021/jm9708588 _2doi
040			_aNLM _beng _cNLM
100	1		_aXu, R
245	0	0	_aSynthesis and pharmacological characterization of O-alkynyloximes of tropinone and N-methylpiperidinone as muscarinic agonists. _h[electronic resource]
260			_bJournal of medicinal chemistry _cAug 1998
300			_a3220-31 p. _bdigital
500			_aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650	0	4	_aAnimals
650	0	4	_aAorta _xdrug effects
650	0	4	_aBinding, Competitive
650	0	4	_aDrug Design
650	0	4	_aEscape Reaction _xdrug effects
650	0	4	_aIn Vitro Techniques
650	0	4	_aMale
650	0	4	_aMaze Learning _xdrug effects
650	0	4	_aMice
650	0	4	_aModels, Molecular
650	0	4	_aMolecular Structure
650	0	4	_aMuscarinic Agonists _xchemical synthesis
650	0	4	_aMuscle Contraction _xdrug effects
650	0	4	_aMuscle, Smooth, Vascular _xdrug effects
650	0	4	_aN-Methylscopolamine _xpharmacology
650	0	4	_aNuclear Magnetic Resonance, Biomolecular
650	0	4	_aPiperidines _xchemical synthesis
650	0	4	_aPirenzepine _xmetabolism
650	0	4	_aRabbits
650	0	4	_aRats
650	0	4	_aRats, Sprague-Dawley
650	0	4	_aReceptors, Muscarinic _xdrug effects
650	0	4	_aStructure-Activity Relationship
650	0	4	_aTropanes _xchemical synthesis
700	1		_aSim, M K
700	1		_aGo, M L
773	0		_tJournal of medicinal chemistry _gvol. 41 _gno. 17 _gp. 3220-31
856	4	0	_uhttps://doi.org/10.1021/jm9708588 _zAvailable from publisher's website
999			_c9669073 _d9669073