| 000 | 01459 a2200361 4500 | ||
|---|---|---|---|
| 005 | 20250513145631.0 | ||
| 264 | 0 | _c19981022 | |
| 008 | 199810s 0 0 eng d | ||
| 022 | _a0192-0561 | ||
| 024 | 7 |
_a10.1016/s0192-0561(97)00075-1 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aHall, M J | |
| 245 | 0 | 0 |
_aLong-term exposure to methotrexate induces immunophenotypic changes, decreased methotrexate uptake and increased dihydrofolate gene copy number in Jurkat T cells. _h[electronic resource] |
| 260 |
_bInternational journal of immunopharmacology _c |
||
| 300 |
_a709-20 p. _bdigital |
||
| 500 | _aPublication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. | ||
| 650 | 0 | 4 |
_aAntigens, Differentiation, T-Lymphocyte _xmetabolism |
| 650 | 0 | 4 | _aGene Dosage |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 |
_aImmunosuppressive Agents _xmetabolism |
| 650 | 0 | 4 |
_aInterleukin-2 _xmetabolism |
| 650 | 0 | 4 | _aJurkat Cells |
| 650 | 0 | 4 |
_aMethotrexate _xmetabolism |
| 650 | 0 | 4 |
_aT-Lymphocytes _xdrug effects |
| 650 | 0 | 4 |
_aTetrahydrofolate Dehydrogenase _xgenetics |
| 700 | 1 | _aLawrence, D A | |
| 700 | 1 | _aLansiedel, J C | |
| 700 | 1 | _aWalsh, A C | |
| 700 | 1 | _aComstock, L L | |
| 700 | 1 | _aKremer, J M | |
| 773 | 0 |
_tInternational journal of immunopharmacology _gvol. 19 _gno. 11-12 _gp. 709-20 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1016/s0192-0561(97)00075-1 _zAvailable from publisher's website |
| 999 |
_c9635182 _d9635182 |
||