000 02119 a2200673 4500
005 20250513145606.0
264 0 _c19980803
008 199808s 0 0 eng d
022 _a0022-2623
024 7 _a10.1021/jm980068d
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aDragovich, P S
245 0 0 _aStructure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 1. Michael acceptor structure-activity studies.
_h[electronic resource]
260 _bJournal of medicinal chemistry
_cJul 1998
300 _a2806-18 p.
_bdigital
500 _aPublication Type: Comparative Study; Journal Article
650 0 4 _a3C Viral Proteases
650 0 4 _aAnimals
650 0 4 _aAntiviral Agents
_xchemical synthesis
650 0 4 _aBinding Sites
650 0 4 _aCell Line, Transformed
650 0 4 _aCrystallography, X-Ray
650 0 4 _aCysteine Endopeptidases
_xchemistry
650 0 4 _aCysteine Proteinase Inhibitors
_xchemical synthesis
650 0 4 _aDrug Design
650 0 4 _aDrug Stability
650 0 4 _aHeLa Cells
650 0 4 _aHumans
650 0 4 _aOligopeptides
_xchemical synthesis
650 0 4 _aProtein Conformation
650 0 4 _aRats
650 0 4 _aRats, Sprague-Dawley
650 0 4 _aRhinovirus
_xdrug effects
650 0 4 _aStructure-Activity Relationship
650 0 4 _aViral Proteins
700 1 _aWebber, S E
700 1 _aBabine, R E
700 1 _aFuhrman, S A
700 1 _aPatick, A K
700 1 _aMatthews, D A
700 1 _aLee, C A
700 1 _aReich, S H
700 1 _aPrins, T J
700 1 _aMarakovits, J T
700 1 _aLittlefield, E S
700 1 _aZhou, R
700 1 _aTikhe, J
700 1 _aFord, C E
700 1 _aWallace, M B
700 1 _aMeador, J W
700 1 _aFerre, R A
700 1 _aBrown, E L
700 1 _aBinford, S L
700 1 _aHarr, J E
700 1 _aDeLisle, D M
700 1 _aWorland, S T
773 0 _tJournal of medicinal chemistry
_gvol. 41
_gno. 15
_gp. 2806-18
856 4 0 _uhttps://doi.org/10.1021/jm980068d
_zAvailable from publisher's website
999 _c9633943
_d9633943