000 | 02186 a2200685 4500 | ||
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005 | 20250513145010.0 | ||
264 | 0 | _c19980724 | |
008 | 199807s 0 0 eng d | ||
022 | _a0022-2623 | ||
024 | 7 |
_a10.1021/jm960683m _2doi |
|
040 |
_aNLM _beng _cNLM |
||
100 | 1 | _aTecle, H | |
245 | 0 | 0 |
_aDesign and synthesis of m1-selective muscarinic agonists: (R)-(-)-(Z)-1-Azabicyclo[2.2.1]heptan-3-one, O-(3-(3'-methoxyphenyl)-2-propynyl)oxime maleate (CI-1017), a functionally m1-selective muscarinic agonist. _h[electronic resource] |
260 |
_bJournal of medicinal chemistry _cJul 1998 |
||
300 |
_a2524-36 p. _bdigital |
||
500 | _aPublication Type: Journal Article | ||
650 | 0 | 4 | _a3T3 Cells |
650 | 0 | 4 | _aAdenylyl Cyclase Inhibitors |
650 | 0 | 4 | _aAnimals |
650 | 0 | 4 |
_aBridged Bicyclo Compounds, Heterocyclic _xchemical synthesis |
650 | 0 | 4 | _aCHO Cells |
650 | 0 | 4 | _aCricetinae |
650 | 0 | 4 | _aDrug Design |
650 | 0 | 4 |
_aEnzyme Inhibitors _xchemical synthesis |
650 | 0 | 4 | _aHumans |
650 | 0 | 4 |
_aInositol Phosphates _xbiosynthesis |
650 | 0 | 4 | _aMale |
650 | 0 | 4 |
_aMemory _xdrug effects |
650 | 0 | 4 | _aMice |
650 | 0 | 4 |
_aMuscarinic Agonists _xchemical synthesis |
650 | 0 | 4 |
_aOximes _xchemical synthesis |
650 | 0 | 4 | _aRats |
650 | 0 | 4 | _aReceptor, Muscarinic M1 |
650 | 0 | 4 |
_aReceptors, Muscarinic _xdrug effects |
650 | 0 | 4 | _aStereoisomerism |
650 | 0 | 4 | _aStructure-Activity Relationship |
650 | 0 | 4 | _aTransfection |
700 | 1 | _aBarrett, S D | |
700 | 1 | _aLauffer, D J | |
700 | 1 | _aAugelli-Szafran, C | |
700 | 1 | _aBrann, M R | |
700 | 1 | _aCallahan, M J | |
700 | 1 | _aCaprathe, B W | |
700 | 1 | _aDavis, R E | |
700 | 1 | _aDoyle, P D | |
700 | 1 | _aEubanks, D | |
700 | 1 | _aLipiniski, W | |
700 | 1 | _aMirzadegan, T | |
700 | 1 | _aMoos, W H | |
700 | 1 | _aMoreland, D W | |
700 | 1 | _aNelson, C B | |
700 | 1 | _aPavia, M R | |
700 | 1 | _aRaby, C | |
700 | 1 | _aSchwarz, R D | |
700 | 1 | _aSpencer, C J | |
700 | 1 | _aThomas, A J | |
700 | 1 | _aJaen, J C | |
773 | 0 |
_tJournal of medicinal chemistry _gvol. 41 _gno. 14 _gp. 2524-36 |
|
856 | 4 | 0 |
_uhttps://doi.org/10.1021/jm960683m _zAvailable from publisher's website |
999 |
_c9617283 _d9617283 |