000 01889 a2200481 4500
005 20250513142521.0
264 0 _c19980608
008 199806s 0 0 eng d
022 _a0003-9861
024 7 _a10.1006/abbi.1998.0615
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aLasker, J M
245 0 0 _aCharacterization of CYP2C19 and CYP2C9 from human liver: respective roles in microsomal tolbutamide, S-mephenytoin, and omeprazole hydroxylations.
_h[electronic resource]
260 _bArchives of biochemistry and biophysics
_cMay 1998
300 _a16-28 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
650 0 4 _aAnti-Inflammatory Agents, Non-Steroidal
_xmetabolism
650 0 4 _aAryl Hydrocarbon Hydroxylases
650 0 4 _aChromatography, DEAE-Cellulose
650 0 4 _aChromatography, Ion Exchange
650 0 4 _aCytochrome P-450 CYP2C19
650 0 4 _aCytochrome P-450 CYP2C8
650 0 4 _aCytochrome P-450 CYP2C9
650 0 4 _aCytochrome P-450 Enzyme System
_xisolation & purification
650 0 4 _aElectrophoresis, Polyacrylamide Gel
650 0 4 _aHumans
650 0 4 _aHydroxylation
650 0 4 _aKinetics
650 0 4 _aMephenytoin
_xpharmacokinetics
650 0 4 _aMicrosomes, Liver
_xenzymology
650 0 4 _aMixed Function Oxygenases
_xisolation & purification
650 0 4 _aOmeprazole
_xpharmacokinetics
650 0 4 _aSteroid 16-alpha-Hydroxylase
650 0 4 _aSteroid Hydroxylases
_xisolation & purification
650 0 4 _aSubstrate Specificity
650 0 4 _aTolbutamide
_xpharmacokinetics
650 0 4 _aUltrafiltration
700 1 _aWester, M R
700 1 _aAramsombatdee, E
700 1 _aRaucy, J L
773 0 _tArchives of biochemistry and biophysics
_gvol. 353
_gno. 1
_gp. 16-28
856 4 0 _uhttps://doi.org/10.1006/abbi.1998.0615
_zAvailable from publisher's website
999 _c9545491
_d9545491