000 01999 a2200589 4500
005 20250513140223.0
264 0 _c19980414
008 199804s 0 0 eng d
022 _a0022-2623
024 7 _a10.1021/jm970427p
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aBarlocco, D
245 0 0 _aMono- and disubstituted-3,8-diazabicyclo[3.2.1]octane derivatives as analgesics structurally related to epibatidine: synthesis, activity, and modeling.
_h[electronic resource]
260 _bJournal of medicinal chemistry
_cFeb 1998
300 _a674-81 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAbdominal Muscles
_xphysiology
650 0 4 _aAnalgesia
650 0 4 _aAnalgesics, Non-Narcotic
_xchemical synthesis
650 0 4 _aAnimals
650 0 4 _aBridged Bicyclo Compounds, Heterocyclic
_xchemical synthesis
650 0 4 _aCerebral Cortex
_xmetabolism
650 0 4 _aHumans
650 0 4 _aKinetics
650 0 4 _aMagnetic Resonance Spectroscopy
650 0 4 _aMale
650 0 4 _aMecamylamine
_xpharmacology
650 0 4 _aMice
650 0 4 _aModels, Molecular
650 0 4 _aMolecular Conformation
650 0 4 _aMuscle Contraction
_xdrug effects
650 0 4 _aNaloxone
_xpharmacology
650 0 4 _aNarcotic Antagonists
_xpharmacology
650 0 4 _aPain Threshold
_xdrug effects
650 0 4 _aPyridazines
_xchemical synthesis
650 0 4 _aPyridines
_xchemistry
650 0 4 _aRats
650 0 4 _aReceptors, Cholinergic
_xdrug effects
700 1 _aCignarella, G
700 1 _aTondi, D
700 1 _aVianello, P
700 1 _aVilla, S
700 1 _aBartolini, A
700 1 _aGhelardini, C
700 1 _aGaleotti, N
700 1 _aAnderson, D J
700 1 _aKuntzweiler, T A
700 1 _aColombo, D
700 1 _aToma, L
773 0 _tJournal of medicinal chemistry
_gvol. 41
_gno. 5
_gp. 674-81
856 4 0 _uhttps://doi.org/10.1021/jm970427p
_zAvailable from publisher's website
999 _c9481373
_d9481373