000 01847 a2200517 4500
005 20250513135225.0
264 0 _c19980317
008 199803s 0 0 eng d
022 _a0022-2623
024 7 _a10.1021/jm970034q
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aHopper, A T
245 0 0 _aDesign, synthesis, and biological evaluation of conformationally constrained aci-reductone mimics of arachidonic acid.
_h[electronic resource]
260 _bJournal of medicinal chemistry
_cFeb 1998
300 _a420-7 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aAnimals
650 0 4 _aAntioxidants
_xchemical synthesis
650 0 4 _aArachidonate 5-Lipoxygenase
_xmetabolism
650 0 4 _aArachidonic Acid
_xchemistry
650 0 4 _aCell Line, Transformed
650 0 4 _aCell Nucleus
_xmetabolism
650 0 4 _aCyclooxygenase 1
650 0 4 _aCyclooxygenase 2
650 0 4 _aCyclooxygenase 2 Inhibitors
650 0 4 _aCyclooxygenase Inhibitors
_xchemical synthesis
650 0 4 _aDrug Design
650 0 4 _aIndicators and Reagents
650 0 4 _aIsoenzymes
_xmetabolism
650 0 4 _aLipopolysaccharides
_xpharmacology
650 0 4 _aLipoxygenase Inhibitors
_xchemical synthesis
650 0 4 _aMacrophages, Peritoneal
_xdrug effects
650 0 4 _aMalondialdehyde
650 0 4 _aMembrane Proteins
650 0 4 _aModels, Molecular
650 0 4 _aMolecular Conformation
650 0 4 _aMolecular Structure
650 0 4 _aNF-kappa B
_xmetabolism
650 0 4 _aProstaglandin-Endoperoxide Synthases
_xmetabolism
650 0 4 _aRats
650 0 4 _aStructure-Activity Relationship
700 1 _aWitiak, D T
700 1 _aZiemniak, J
773 0 _tJournal of medicinal chemistry
_gvol. 41
_gno. 4
_gp. 420-7
856 4 0 _uhttps://doi.org/10.1021/jm970034q
_zAvailable from publisher's website
999 _c9452688
_d9452688