000 01450 a2200385 4500
005 20250513132518.0
264 0 _c19980130
008 199801s 0 0 eng d
022 _a0022-2836
024 7 _a10.1006/jmbi.1997.1427
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aMaga, G
245 0 0 _aResistance to nevirapine of HIV-1 reverse transcriptase mutants: loss of stabilizing interactions and thermodynamic or steric barriers are induced by different single amino acid substitutions.
_h[electronic resource]
260 _bJournal of molecular biology
_cDec 1997
300 _a738-47 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAnti-HIV Agents
_xmetabolism
650 0 4 _aDrug Resistance, Microbial
650 0 4 _aHIV Reverse Transcriptase
_xantagonists & inhibitors
650 0 4 _aHIV-1
_xdrug effects
650 0 4 _aHumans
650 0 4 _aKinetics
650 0 4 _aMutation
_xphysiology
650 0 4 _aNevirapine
_xmetabolism
650 0 4 _aProtein Binding
650 0 4 _aRecombinant Fusion Proteins
650 0 4 _aReverse Transcriptase Inhibitors
_xmetabolism
650 0 4 _aThermodynamics
700 1 _aAmacker, M
700 1 _aRuel, N
700 1 _aHübscher, U
700 1 _aSpadari, S
773 0 _tJournal of molecular biology
_gvol. 274
_gno. 5
_gp. 738-47
856 4 0 _uhttps://doi.org/10.1006/jmbi.1997.1427
_zAvailable from publisher's website
999 _c9374760
_d9374760