000 01735 a2200469 4500
005 20250513132435.0
264 0 _c19980107
008 199801s 0 0 eng d
022 _a0009-2797
024 7 _a10.1016/s0009-2797(97)00071-9
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aLi, A P
245 0 0 _aPrimary human hepatocytes as a tool for the evaluation of structure-activity relationship in cytochrome P450 induction potential of xenobiotics: evaluation of rifampin, rifapentine and rifabutin.
_h[electronic resource]
260 _bChemico-biological interactions
_cNov 1997
300 _a17-30 p.
_bdigital
500 _aPublication Type: Comparative Study; Journal Article
650 0 4 _aAntibiotics, Antitubercular
_xmetabolism
650 0 4 _aAntitubercular Agents
_xmetabolism
650 0 4 _aCytochrome P-450 Enzyme System
_xbiosynthesis
650 0 4 _aDrug Evaluation, Preclinical
_xmethods
650 0 4 _aEnzyme Induction
_xdrug effects
650 0 4 _aGlucuronates
_xmetabolism
650 0 4 _aHumans
650 0 4 _aHydroxylation
650 0 4 _aIsoenzymes
_xbiosynthesis
650 0 4 _aLiver
_xcytology
650 0 4 _aRifabutin
_xmetabolism
650 0 4 _aRifampin
_xanalogs & derivatives
650 0 4 _aStructure-Activity Relationship
650 0 4 _aTestosterone
_xmetabolism
650 0 4 _aTime Factors
650 0 4 _aZidovudine
_xmetabolism
700 1 _aReith, M K
700 1 _aRasmussen, A
700 1 _aGorski, J C
700 1 _aHall, S D
700 1 _aXu, L
700 1 _aKaminski, D L
700 1 _aCheng, L K
773 0 _tChemico-biological interactions
_gvol. 107
_gno. 1-2
_gp. 17-30
856 4 0 _uhttps://doi.org/10.1016/s0009-2797(97)00071-9
_zAvailable from publisher's website
999 _c9372583
_d9372583