000 | 02046 a2200613 4500 | ||
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005 | 20250513132243.0 | ||
264 | 0 | _c19980112 | |
008 | 199801s 0 0 eng d | ||
022 | _a0022-2623 | ||
024 | 7 |
_a10.1021/jm970517u _2doi |
|
040 |
_aNLM _beng _cNLM |
||
100 | 1 | _aSelnick, H G | |
245 | 0 | 0 |
_aClass III antiarrhythmic activity in vivo by selective blockade of the slowly activating cardiac delayed rectifier potassium current IKs by (R)-2-(2,4-trifluoromethyl)-N-[2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)- 2, 3-dihydro-1H-benzo[e][1,4]diazepin-3-yl]acetamide. _h[electronic resource] |
260 |
_bJournal of medicinal chemistry _cNov 1997 |
||
300 |
_a3865-8 p. _bdigital |
||
500 | _aPublication Type: Journal Article | ||
650 | 0 | 4 |
_aAcetamides _xchemical synthesis |
650 | 0 | 4 | _aAdministration, Oral |
650 | 0 | 4 | _aAnimals |
650 | 0 | 4 |
_aAnti-Arrhythmia Agents _xchemical synthesis |
650 | 0 | 4 |
_aBenzodiazepinones _xchemical synthesis |
650 | 0 | 4 | _aCells, Cultured |
650 | 0 | 4 | _aDogs |
650 | 0 | 4 |
_aElectrocardiography, Ambulatory _xdrug effects |
650 | 0 | 4 | _aGuinea Pigs |
650 | 0 | 4 |
_aHeart _xdrug effects |
650 | 0 | 4 | _aHumans |
650 | 0 | 4 |
_aMyocardium _xcytology |
650 | 0 | 4 | _aPotassium Channel Blockers |
650 | 0 | 4 |
_aPotassium Channels _xphysiology |
650 | 0 | 4 | _aXenopus |
700 | 1 | _aLiverton, N J | |
700 | 1 | _aBaldwin, J J | |
700 | 1 | _aButcher, J W | |
700 | 1 | _aClaremon, D A | |
700 | 1 | _aElliott, J M | |
700 | 1 | _aFreidinger, R M | |
700 | 1 | _aKing, S A | |
700 | 1 | _aLibby, B E | |
700 | 1 | _aMcIntyre, C J | |
700 | 1 | _aPribush, D A | |
700 | 1 | _aRemy, D C | |
700 | 1 | _aSmith, G R | |
700 | 1 | _aTebben, A J | |
700 | 1 | _aJurkiewicz, N K | |
700 | 1 | _aLynch, J J | |
700 | 1 | _aSalata, J J | |
700 | 1 | _aSanguinetti, M C | |
700 | 1 | _aSiegl, P K | |
700 | 1 | _aSlaughter, D E | |
700 | 1 | _aVyas, K | |
773 | 0 |
_tJournal of medicinal chemistry _gvol. 40 _gno. 24 _gp. 3865-8 |
|
856 | 4 | 0 |
_uhttps://doi.org/10.1021/jm970517u _zAvailable from publisher's website |
999 |
_c9366851 _d9366851 |