000 02089 a2200589 4500
005 20250513132140.0
264 0 _c19980127
008 199801s 0 0 eng d
022 _a0090-9556
040 _aNLM
_beng
_cNLM
100 1 _aKoenigs, L L
245 0 0 _aMechanism-based inactivation of human liver cytochrome P450 2A6 by 8-methoxypsoralen.
_h[electronic resource]
260 _bDrug metabolism and disposition: the biological fate of chemicals
_cDec 1997
300 _a1407-15 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
650 0 4 _aAdolescent
650 0 4 _aAdult
650 0 4 _aAryl Hydrocarbon Hydroxylases
650 0 4 _aChild
650 0 4 _aCoumarins
_xmetabolism
650 0 4 _aCytochrome P-450 CYP1A2
650 0 4 _aCytochrome P-450 CYP1A2 Inhibitors
650 0 4 _aCytochrome P-450 CYP2A6
650 0 4 _aCytochrome P-450 CYP2C19
650 0 4 _aCytochrome P-450 CYP2D6 Inhibitors
650 0 4 _aCytochrome P-450 CYP2E1 Inhibitors
650 0 4 _aCytochrome P-450 CYP3A
650 0 4 _aCytochrome P-450 Enzyme Inhibitors
650 0 4 _aCytochrome P-450 Enzyme System
_xgenetics
650 0 4 _aCytochromes b5
_xmetabolism
650 0 4 _aEnzyme Activation
_xdrug effects
650 0 4 _aFemale
650 0 4 _aHumans
650 0 4 _aKinetics
650 0 4 _aMale
650 0 4 _aMethoxsalen
_xpharmacology
650 0 4 _aMicrosomes, Liver
_xdrug effects
650 0 4 _aMiddle Aged
650 0 4 _aMixed Function Oxygenases
_xantagonists & inhibitors
650 0 4 _aNADP
_xmetabolism
650 0 4 _aNADPH-Ferrihemoprotein Reductase
_xmetabolism
650 0 4 _aRecombinant Proteins
_xisolation & purification
650 0 4 _aSpectrophotometry
650 0 4 _aSteroid 16-alpha-Hydroxylase
650 0 4 _aSteroid Hydroxylases
_xantagonists & inhibitors
650 0 4 _aTime Factors
700 1 _aPeter, R M
700 1 _aThompson, S J
700 1 _aRettie, A E
700 1 _aTrager, W F
773 0 _tDrug metabolism and disposition: the biological fate of chemicals
_gvol. 25
_gno. 12
_gp. 1407-15
999 _c9363723
_d9363723