000 01959 a2200577 4500
005 20250513130030.0
264 0 _c19971113
008 199711s 0 0 eng d
022 _a0009-9236
024 7 _a10.1016/S0009-9236(97)90031-X
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aOdani, A
245 0 0 _aGenetic polymorphism of the CYP2C subfamily and its effect on the pharmacokinetics of phenytoin in Japanese patients with epilepsy.
_h[electronic resource]
260 _bClinical pharmacology and therapeutics
_cSep 1997
300 _a287-92 p.
_bdigital
500 _aPublication Type: Clinical Trial; Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAdolescent
650 0 4 _aAdult
650 0 4 _aAnticonvulsants
_xpharmacokinetics
650 0 4 _aAryl Hydrocarbon Hydroxylases
650 0 4 _aBayes Theorem
650 0 4 _aChild
650 0 4 _aChild, Preschool
650 0 4 _aCytochrome P-450 CYP2C19
650 0 4 _aCytochrome P-450 CYP2C9
650 0 4 _aCytochrome P-450 Enzyme System
_xchemistry
650 0 4 _aEpilepsy
_xdrug therapy
650 0 4 _aFemale
650 0 4 _aGene Expression Regulation, Enzymologic
_xgenetics
650 0 4 _aGenotype
650 0 4 _aHeterozygote
650 0 4 _aHumans
650 0 4 _aInfant
650 0 4 _aJapan
650 0 4 _aMale
650 0 4 _aMixed Function Oxygenases
_xchemistry
650 0 4 _aMutation
_xgenetics
650 0 4 _aPhenytoin
_xblood
650 0 4 _aPolymerase Chain Reaction
650 0 4 _aPolymorphism, Genetic
650 0 4 _aSteroid 16-alpha-Hydroxylase
650 0 4 _aSteroid Hydroxylases
_xchemistry
700 1 _aHashimoto, Y
700 1 _aOtsuki, Y
700 1 _aUwai, Y
700 1 _aHattori, H
700 1 _aFurusho, K
700 1 _aInui, K
773 0 _tClinical pharmacology and therapeutics
_gvol. 62
_gno. 3
_gp. 287-92
856 4 0 _uhttps://doi.org/10.1016/S0009-9236(97)90031-X
_zAvailable from publisher's website
999 _c9305549
_d9305549