000 | 01663 a2200445 4500 | ||
---|---|---|---|
005 | 20250513113745.0 | ||
264 | 0 | _c19970417 | |
008 | 199704s 0 0 eng d | ||
022 | _a0007-0920 | ||
024 | 7 |
_a10.1038/bjc.1997.176 _2doi |
|
040 |
_aNLM _beng _cNLM |
||
100 | 1 | _aDesiderio, M A | |
245 | 0 | 0 |
_aTreatment with inhibitors of polyamine biosynthesis, which selectively lower intracellular spermine, does not affect the activity of alkylating agents but antagonizes the cytotoxicity of DNA topoisomerase II inhibitors. _h[electronic resource] |
260 |
_bBritish journal of cancer _c1997 |
||
300 |
_a1028-34 p. _bdigital |
||
500 | _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't | ||
650 | 0 | 4 | _aAlkynes |
650 | 0 | 4 |
_aAntineoplastic Agents, Alkylating _xpharmacology |
650 | 0 | 4 |
_aCell Cycle _xdrug effects |
650 | 0 | 4 |
_aCell Survival _xdrug effects |
650 | 0 | 4 |
_aDNA, Neoplasm _xbiosynthesis |
650 | 0 | 4 |
_aDeoxyadenosines _xpharmacology |
650 | 0 | 4 |
_aDiamines _xpharmacology |
650 | 0 | 4 |
_aEnzyme Inhibitors _xpharmacology |
650 | 0 | 4 | _aFemale |
650 | 0 | 4 | _aHumans |
650 | 0 | 4 | _aOrnithine Decarboxylase Inhibitors |
650 | 0 | 4 | _aOvarian Neoplasms |
650 | 0 | 4 |
_aPolyamines _xmetabolism |
650 | 0 | 4 |
_aSpermine _xmetabolism |
650 | 0 | 4 | _aTopoisomerase II Inhibitors |
650 | 0 | 4 | _aTumor Cells, Cultured |
700 | 1 | _aBergamaschi, D | |
700 | 1 | _aMascellani, E | |
700 | 1 | _aDe Feudis, P | |
700 | 1 | _aErba, E | |
700 | 1 | _aD'Incalci, M | |
773 | 0 |
_tBritish journal of cancer _gvol. 75 _gno. 7 _gp. 1028-34 |
|
856 | 4 | 0 |
_uhttps://doi.org/10.1038/bjc.1997.176 _zAvailable from publisher's website |
999 |
_c9068052 _d9068052 |