| 000 | 01620 a2200529 4500 | ||
|---|---|---|---|
| 005 | 20250513110641.0 | ||
| 264 | 0 | _c19970130 | |
| 008 | 199701s 0 0 eng d | ||
| 022 | _a0006-2960 | ||
| 024 | 7 |
_a10.1021/bi9616108 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aTsiang, M | |
| 245 | 0 | 0 |
_aProtein engineering thrombin for optimal specificity and potency of anticoagulant activity in vivo. _h[electronic resource] |
| 260 |
_bBiochemistry _cDec 1996 |
||
| 300 |
_a16449-57 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article | ||
| 650 | 0 | 4 | _aAnimals |
| 650 | 0 | 4 |
_aAnticoagulants _xpharmacology |
| 650 | 0 | 4 |
_aBlood Coagulation _xdrug effects |
| 650 | 0 | 4 | _aDrug Evaluation, Preclinical |
| 650 | 0 | 4 |
_aFibrinogen _xmetabolism |
| 650 | 0 | 4 | _aHalf-Life |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 | _aKinetics |
| 650 | 0 | 4 | _aMacaca fascicularis |
| 650 | 0 | 4 | _aModels, Molecular |
| 650 | 0 | 4 | _aMutagenesis, Site-Directed |
| 650 | 0 | 4 |
_aPlatelet Activation _xdrug effects |
| 650 | 0 | 4 |
_aProtein C _xmetabolism |
| 650 | 0 | 4 | _aProtein Conformation |
| 650 | 0 | 4 | _aProtein Engineering |
| 650 | 0 | 4 | _aSubstrate Specificity |
| 650 | 0 | 4 |
_aThrombin _xgenetics |
| 700 | 1 | _aPaborsky, L R | |
| 700 | 1 | _aLi, W X | |
| 700 | 1 | _aJain, A K | |
| 700 | 1 | _aMao, C T | |
| 700 | 1 | _aDunn, K E | |
| 700 | 1 | _aLee, D W | |
| 700 | 1 | _aMatsumura, S Y | |
| 700 | 1 | _aMatteucci, M D | |
| 700 | 1 | _aCoutré, S E | |
| 700 | 1 | _aLeung, L L | |
| 700 | 1 | _aGibbs, C S | |
| 773 | 0 |
_tBiochemistry _gvol. 35 _gno. 51 _gp. 16449-57 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1021/bi9616108 _zAvailable from publisher's website |
| 999 |
_c8979422 _d8979422 |
||