000 01640 a2200409 4500
005 20250513103205.0
264 0 _c19970212
008 199702s 0 0 eng d
022 _a0090-9556
040 _aNLM
_beng
_cNLM
100 1 _aFeierman, D E
245 0 0 _aMetabolism of fentanyl, a synthetic opioid analgesic, by human liver microsomes. Role of CYP3A4.
_h[electronic resource]
260 _bDrug metabolism and disposition: the biological fate of chemicals
_cSep 1996
300 _a932-9 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
650 0 4 _aAnalgesics, Opioid
_xmetabolism
650 0 4 _aAryl Hydrocarbon Hydroxylases
650 0 4 _aCytochrome P-450 CYP1A2
_xmetabolism
650 0 4 _aCytochrome P-450 CYP2C8
650 0 4 _aCytochrome P-450 CYP2C9
650 0 4 _aCytochrome P-450 CYP3A
650 0 4 _aCytochrome P-450 Enzyme Inhibitors
650 0 4 _aCytochrome P-450 Enzyme System
_xmetabolism
650 0 4 _aFentanyl
_xanalogs & derivatives
650 0 4 _aGas Chromatography-Mass Spectrometry
650 0 4 _aHumans
650 0 4 _aKetoconazole
_xpharmacology
650 0 4 _aKinetics
650 0 4 _aMicrosomes, Liver
_xenzymology
650 0 4 _aMixed Function Oxygenases
_xantagonists & inhibitors
650 0 4 _aSteroid 16-alpha-Hydroxylase
650 0 4 _aSteroid Hydroxylases
_xmetabolism
650 0 4 _aTheophylline
_xanalogs & derivatives
650 0 4 _aTolbutamide
_xpharmacology
700 1 _aLasker, J M
773 0 _tDrug metabolism and disposition: the biological fate of chemicals
_gvol. 24
_gno. 9
_gp. 932-9
999 _c8879260
_d8879260