000 | 01286 a2200373 4500 | ||
---|---|---|---|
005 | 20250513100600.0 | ||
264 | 0 | _c19970204 | |
008 | 199702s 0 0 eng d | ||
022 | _a1074-5521 | ||
024 | 7 |
_a10.1016/s1074-5521(96)90108-8 _2doi |
|
040 |
_aNLM _beng _cNLM |
||
100 | 1 | _aHung, D T | |
245 | 0 | 0 |
_a(+)-Discodermolide binds to microtubules in stoichiometric ratio to tubulin dimers, blocks taxol binding and results in mitotic arrest. _h[electronic resource] |
260 |
_bChemistry & biology _cApr 1996 |
||
300 |
_a287-93 p. _bdigital |
||
500 | _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. | ||
650 | 0 | 4 | _a3T3 Cells |
650 | 0 | 4 | _aAlkanes |
650 | 0 | 4 | _aAnimals |
650 | 0 | 4 | _aBinding Sites |
650 | 0 | 4 | _aCarbamates |
650 | 0 | 4 | _aCell Line |
650 | 0 | 4 | _aHumans |
650 | 0 | 4 |
_aLactones _xmetabolism |
650 | 0 | 4 | _aMice |
650 | 0 | 4 |
_aMicrotubules _xmetabolism |
650 | 0 | 4 |
_aMitosis _xdrug effects |
650 | 0 | 4 |
_aPaclitaxel _xantagonists & inhibitors |
650 | 0 | 4 | _aPyrones |
700 | 1 | _aChen, J | |
700 | 1 | _aSchreiber, S L | |
773 | 0 |
_tChemistry & biology _gvol. 3 _gno. 4 _gp. 287-93 |
|
856 | 4 | 0 |
_uhttps://doi.org/10.1016/s1074-5521(96)90108-8 _zAvailable from publisher's website |
999 |
_c8802556 _d8802556 |