000 01895 a2200529 4500
005 20250513093242.0
264 0 _c19960910
008 199609s 0 0 eng d
022 _a0270-9139
024 7 _a10.1002/hep.510240134
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aLekehal, M
245 0 0 _aHepatotoxicity of the herbal medicine germander: metabolic activation of its furano diterpenoids by cytochrome P450 3A Depletes cytoskeleton-associated protein thiols and forms plasma membrane blebs in rat hepatocytes.
_h[electronic resource]
260 _bHepatology (Baltimore, Md.)
_cJul 1996
300 _a212-8 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAcetylcysteine
_xpharmacology
650 0 4 _aAnimals
650 0 4 _aBiotransformation
650 0 4 _aCell Membrane
_xdrug effects
650 0 4 _aCysteine
_xpharmacology
650 0 4 _aCystine
_xpharmacology
650 0 4 _aCytochrome P-450 CYP2E1
650 0 4 _aCytochrome P-450 Enzyme System
_xmetabolism
650 0 4 _aCytoskeleton
_xdrug effects
650 0 4 _aDexamethasone
_xpharmacology
650 0 4 _aDiterpenes
_xmetabolism
650 0 4 _aDiterpenes, Clerodane
650 0 4 _aFemale
650 0 4 _aGlutathione
_xmetabolism
650 0 4 _aLiver
_xdrug effects
650 0 4 _aMale
650 0 4 _aMixed Function Oxygenases
_xmetabolism
650 0 4 _aPhytotherapy
650 0 4 _aPlant Extracts
_xmetabolism
650 0 4 _aRats
650 0 4 _aRats, Sprague-Dawley
650 0 4 _aSpiro Compounds
_xmetabolism
650 0 4 _aTroleandomycin
_xpharmacology
700 1 _aPessayre, D
700 1 _aLereau, J M
700 1 _aMoulis, C
700 1 _aFouraste, I
700 1 _aFau, D
773 0 _tHepatology (Baltimore, Md.)
_gvol. 24
_gno. 1
_gp. 212-8
856 4 0 _uhttps://doi.org/10.1002/hep.510240134
_zAvailable from publisher's website
999 _c8704508
_d8704508