000 01510 a2200433 4500
005 20250513090516.0
264 0 _c19960614
008 199606s 0 0 eng d
022 _a0041-1345
040 _aNLM
_beng
_cNLM
100 1 _aJohnson, E M
245 0 0 _aA randomized, double-blind, placebo-controlled study of the safety, tolerance, and preliminary pharmacokinetics of ascending single doses of orally administered sirolimus (rapamycin) in stable renal transplant recipients.
_h[electronic resource]
260 _bTransplantation proceedings
_cApr 1996
300 _a987 p.
_bdigital
500 _aPublication Type: Clinical Trial; Clinical Trial, Phase I; Journal Article; Randomized Controlled Trial
650 0 4 _aAdministration, Oral
650 0 4 _aCyclosporine
_xtherapeutic use
650 0 4 _aDose-Response Relationship, Drug
650 0 4 _aDouble-Blind Method
650 0 4 _aDrug Therapy, Combination
650 0 4 _aHeadache
650 0 4 _aHumans
650 0 4 _aImmunosuppressive Agents
_xadverse effects
650 0 4 _aPlacebos
650 0 4 _aPolyenes
_xadverse effects
650 0 4 _aSirolimus
700 1 _aZimmerman, J
700 1 _aDuderstadt, K
700 1 _aChambers, J
700 1 _aSorenson, A L
700 1 _aGranger, D K
700 1 _aAlmond, P S
700 1 _aFryer, J p
700 1 _aLeventhal, J R
700 1 _aScarola, J
700 1 _aMatas, A J
700 1 _aCanafax, D M
773 0 _tTransplantation proceedings
_gvol. 28
_gno. 2
_gp. 987
999 _c8622535
_d8622535