000 01600 a2200445 4500
005 20250513084651.0
264 0 _c19960301
008 199603s 0 0 eng d
022 _a0022-2623
024 7 _a10.1021/jm9500885
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aLi, Y
245 0 0 _aSynthesis and antitumor evaluation of a highly potent cytotoxic DNA cross-linking polyamine analogue, 1,12-diaziridinyl-4,9-diazadodecane.
_h[electronic resource]
260 _bJournal of medicinal chemistry
_cJan 1996
300 _a339-41 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
650 0 4 _aAnimals
650 0 4 _aAntineoplastic Agents
_xadministration & dosage
650 0 4 _aAziridines
_xadministration & dosage
650 0 4 _aCross-Linking Reagents
_xchemical synthesis
650 0 4 _aDNA
_xdrug effects
650 0 4 _aElectrophoresis, Agar Gel
650 0 4 _aFemale
650 0 4 _aLeukemia L1210
_xdrug therapy
650 0 4 _aMechlorethamine
_xpharmacology
650 0 4 _aMelphalan
_xpharmacology
650 0 4 _aMice
650 0 4 _aMice, Inbred Strains
650 0 4 _aSpermine
_xadministration & dosage
650 0 4 _aThiotepa
_xpharmacology
700 1 _aEiseman, J L
700 1 _aSentz, D L
700 1 _aRogers, F A
700 1 _aPan, S S
700 1 _aHu, L T
700 1 _aEgorin, M J
700 1 _aCallery, P S
773 0 _tJournal of medicinal chemistry
_gvol. 39
_gno. 1
_gp. 339-41
856 4 0 _uhttps://doi.org/10.1021/jm9500885
_zAvailable from publisher's website
999 _c8567897
_d8567897